• Antioxidant and Anti-Inflammatory Activities of Barettin 

      Lind, Karianne Fredenfeldt; Hansen, Espen; Østerud, Bjarne; Eilertsen, Karl-Erik; Bayer, Annette; Engqvist, Stig Olov Magnus; Leszczak, Kinga; Jørgensen, Trond Ø.; Andersen, Jeanette hammer (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      In this paper, we present novel bioactivity for barettin isolated from the marine sponge Geodia barretti. We found that barettin showed strong antioxidant activity in biochemical assays as well as in a lipid peroxidation cell assay. A de-brominated synthetic analogue of barettin did not show the same activity in the antioxidant cell assay, indicating that bromine is important for cellular activity. ...
    • Isolation and Synthesis of Pulmonarins A and B, Acetylcholinesterase Inhibitors from the Colonial Ascidian Synoicum pulmonaria 

      Tadesse, Margey; Svenson, Johan; Sepcič, Kristina; Trembleau, Laurent; Engqvist, Stig Olov Magnus; Andersen, Jeanette Hammer; Jaspars, Marcel; Stensvåg, Klara; Haug, Tor (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-02-14)
      Pulmonarins A and B are two new dibrominated marine acetylcholinesterase inhibitors that were isolated and characterized from the sub-Arctic ascidian <i>Synoicum pulmonaria</i> collected off the Norwegian coast. The structures of natural pulmonarins A and B were tentatively elucidated by spectroscopic methods and later verified by comparison with synthetically prepared material. Both pulmonarins A ...
    • Sensitive on-chip methane detection with a cryptophane-A cladded Mach-Zehnder interferometer 

      Dullo, Firehun Tsige; Lindecrantz, Susan; Jagerska, Jana; Hansen, Jørn H; Engqvist, Stig Olov Magnus; Solbø, Stian; Hellesø, Olav Gaute (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-11-24)
      We report a methane sensor based on an integrated Mach-Zehnder interferometer, which is cladded by a styrene-acrylonitrile film incorporating cryptophane-A. Cryptophane-A is a supramolecular compound able to selectively trap methane, and its presence in the cladding leads to a 17-fold sensitivity enhancement. Our approach, based on 3 cm-long low-loss Si3N4 rib waveguides, results in a detection limit ...